After trying many different ways of sorting and reorganizing my books, including a short lived attempt with the Dewey decimal system, I decided on a semi-sorted, semi-alphabetical, put things where they fit type of setup.
How about you? Are your fictions separate from your non-fictions? Or do you prefer to separate the have read books from the will read books? When all else fails do you stick with alphabetizing?
Let me know in the comments.